THE RATZKE LAB...

...aims to understand, predict, and engineer microbial communities by integrating laboratory experiments with mathematical modeling. Microbes are ubiquitous, including within and on our bodies, where they play a crucial role in health and well-being. Despite their significance, much remains unknown about how these communities function. Our lab focuses on uncovering the fundamental principles that govern microbial interactions and their impact on community structure and function. By deepening this understanding, we aim to design and optimize microbial communities for medical and biotechnological applications.

THE RATZKE LAB...

NEWS

August, 2025: We got a new paper out in ISME J . Bacteria can produce an externalized memory by modifying their environment.

May, 2025: New preprint! Weirdly, biodiversity of microbial communities tends to decrease with increasing nutrient diversity. But, we figured out why.

April, 2025: We got a new paper out in Nature Communications showing how communities can alter (and completely stop) microbial invasions in complex yet predictable ways.

February, 2025: Welcome Sunaina and Anna. Sunaina and Anna joined our lab as PhD students. Sunaina aims to reconstruct microbial interaction networks in complex communities and Anna will develop methods to investigate microbes in very high-throughput.

news archive

RECENT SELECTED PUBLICATIONS

S. Gajrani , X. Ye , C. Ratzke
"Environment-mediated interactions cause an externalized and collective memory in bacteria"
ISME J wraf173 (2025)

X. Ye, O. Shalev, C. Ratzke
"Biotic resistance predictably shifts microbial invasion regimes"
Nature Communications 16, 3952 (2025)

C. Ratzke*, J. Barrere*, J. Gore
"Strength of species interactions determines biodiversity and stability in microbial communities"
Nature Ecology and Evolution 4, 376–383 (2020)

C. Ratzke*, J.Denk*, J.Gore
"Ecological suicide in microbes"
Nature Ecology and Evolution 2, 867–872 (2018)

C. Ratzke, J. Gore
“Modifying and reacting to the environmental pH can drive bacterial interactions”
PLOS Biology 16(3): e2004248 (2018)